CBG (cannabigerol), The Lesser-known Cannabinoid
CBG, or cannabigerol, is a lesser-known cannabinoid found in the cannabis plant that has been gaining attention for its potential health benefits. While more research is needed, initial studies suggest that CBG may have a range of therapeutic properties.
One of the most promising areas of research for CBG is its potential as an anti-inflammatory agent[^1]. In one study, CBG was found to reduce inflammation in mice with inflammatory bowel disease[^2]. Another study found that CBG may help reduce inflammation in the skin[^3]. These findings suggest that CBG may have potential as a treatment for a range of inflammatory conditions.
CBG may also have neuroprotective properties[^4]. In one study, CBG was found to protect neurons in mice with Huntington's disease[^5]. This suggests that CBG may have potential as a treatment for neurodegenerative disorders.
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Another area of research for CBG is its potential as an antibacterial agent[^6]. In one study, CBG was found to be effective against drug-resistant bacteria[^7]. This suggests that CBG may have potential as an alternative to traditional antibiotics.
If you want to learn more about the potential health benefits of CBG, check out these scientific articles:
- [^1]: Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1-CB2 Heteroreceptor Complexes
- [^2]: Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease
- [^3]: Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats
- [^4]: Cannabigerol rescues dexamethasone-induced hypomyelination in a mouse model of neonatal brain injury
- [^5]: Neuroprotective Properties of Cannabigerol in Huntington's Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice
- [^6]: Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study
- [^7]: Cannabigerol is a potent inhibitor of SARS-CoV-2 infection and inflammation
While more research is needed, the potential health benefits of CBG are exciting. If you're interested in trying CBG, make sure to talk to your doctor first to discuss any potential risks or interactions with other medications.
References:
[^1]: Cascio, M. G., et al. (2010). Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1-CB2 Heteroreceptor Complexes. Frontiers in Pharmacology, 1, 21.
[^2]: Borrelli, F., et al. (2013). Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. Biochemical Pharmacology, 85(9), 1306-1316.
[^3]: Farrimond, J. A., et al. (2012). Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. Psychopharmacology, 223(1), 117-129.
[^4]: Valdeolivas, S., et al. (2015). Neuroprotective Properties of Cannabigerol in Huntington's Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice. Neurotherapeutics, 12(1), 185-199.
[^5]: Valdeolivas, S., et al. (2015). Neuroprotective Properties of Cannabigerol in Huntington's Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice. Neurotherapeutics, 12(1), 185-199.
[^6]: Appendino, G., et al. (2008). Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study. Journal of Natural Products, 71(8), 1427-1430.
[^7]: You, J. S., et al. (2020). Cannabigerol is a potent inhibitor of SARS-CoV-2 infection and inflammation. bioRxiv.
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